Day 1 :
University of Rochester, USA
Keynote: Differential diagnosis of anterior crossbite is the first step of early intervention of class III malocclusion
Time : 09:15-09:45
Aliakbar Bahreman graduated from Tehran University in 1961. He did his Pediatric Dentistry Fellowship in 1964 and Specialty in Orthodontic and Dentofacial Orthopedic. He did his MS from Eastman Institute for Oral Health, University of Rochester, New York in 1967. He was the Dean of Dental School, Chair and Founder of both Orthodontic and Pediatric Dentistry departments, National University of Iran from 1967 to 1999. Currently, he is a Clinical Professor at Eastman Institute for Oral Health, University of Rochester, NY. He has more than 14 published papers in national and international journals and serving as an Editorial Board Member of some journals. He is the Author of the book “Early Age Orthodontic Treatment”.
Anterior crossbite is a common problem frequently seen in the primary, mixed or permanent dentition and certainly needs early intervention to prevent further damage to occlusal structures and adverse growth effects to the dentition and basal bones. Anterior cross bite is one of the main symptoms of overall sagittal dentofacial anomalies that can be caused by different structural deformity. Therefore early recognition and differential diagnosis are the first steps toward effective treatment. Generally there are five kinds of anterior crossbites: (1) Simple dental crossbite, (2) Functional crossbite (pseudo class III), (3) Dento-alveolar crossbite, (4) Potential class III, and (5) Skeletal Class III malocclusion. Depending on the origin of the anterior crossbite, and their morphology, etiology and the patient's age, there are several treatment options ranging from simple removable appliance, or comprehensive fixed therapy, to orthopedic approach or orthognathic surgery. The objectives of this presentation are: To inform dental professionals about the etiology, diagnostic criteria and best treatment options of various anterior cross bites; To illustrate simple effective treatment methods for each kind of anterior crossbite from primary and mixed dentition, to non-surgical treatment at permanent dentition. The main goal of this presentation is to highlighting the advantages of early intervention.
Canada China Child Health Foundation, Canada
Time : 09:45-10:15
T P Chiang is the President of Canada China Child Health Foundation, Canada. She has done her BSc, DDS and Doctorate in Dental Medicine from Dalhousie University, Canada. She has completed her Master of Science in Epidemiology from Harvard University. She did her Post-doctoral studies at Massachusetts Institute of Technology, Boston Children's Hospital in Pediatric Dentistry. She is a Professor at University of British Columbia, Beijing Children's Hospital, Beijing Institute of Pediatrics and Children's Hospital of Harbin. She is the Honorary President of Nanjing Medical University Dental Hospital, Consultant at child health hospitals of Guangzhou, Suzhou Health College, and Chongqing Medical University.
Cleft lip and palate is a common congenital maxillofacial deformity, with incidence rate varying among different ethnic groups. There is serious tissue defects with loss of maxillary bone segment and tissue displacement involved, affecting both appearance and function. This deformity causes major challenges because of associated problems, i.e., feeding, conduct disorder high treatment cost, ear infection, hearing loss, language difficulty. With the advancement of science and technology, new surgical techniques and treatments greatly improve the effectiveness of treatment of cleft lip and palate. Current approach to cleft lip and palate treatment is beyond simple surgical repair which include restoration of appearance and function, psychological problem, and changes in growth and developments. Optimal management utilizing an integrated and collaborative and multidisciplinary approach is particularly important and is almost standardized in US and Canada. This collaborative team involves: plastic surgeon, anesthesiologist, pediatric dentist, orthodontist, maxillofacial surgeon, dental surgeon, speech pathologist, audiologist, feeding nurse, pediatrician and otolaryngologist. Dentistry’s role involves the following disciplines: pediatric dentist, orthodontist, maxillofacial surgeon, and prosthodontist. Cleft lip and palate sequential treatment approaches different growth stages with different therapeutic targets. Neonatal period pursue physical appearance and functionality; pre-pubertal period guide arch form development and completion of alveolar bone graft; puberty aims at improve function; orthognathic surgery repair occur following growth and development completion. With respect to the various dental specialties the following are their roles in the treatment of cleft patients; Maxillofacial surgeon: Performs secondary alveolar bone grafts, combines with the orthodontist to correct facial skeletal deformities, augments bone and places implants with the prosthodontist. Prosthodontist: Coordinate with the orthodontist and surgeon during treatment planning, replace missing teeth, restore esthetics, and assure longevity of functional dentition. Orthodontist: Works with the pediatric dentist in the mixed dentition, guidance for the permanent occlusion and maxillo-facial complex, treats the permanent dentition, develops treatment plan for orthognathic surgery with the oral-maxillofacial surgeon and the prosthodontist. Pediatric Dentist: Serves as patient plus parent advocate in infancy and mixed dentition phase treatment , provide unique perspective of the whole child and the preparation of early and overall dental treatment plan (with the team), and finally, its integration and implementation. This program was initially introduced to China in 1999 through multiple exchange programs with Canada and the US. Over the past decade there has been close to 3000 cleft lip and palate patients treated at the Guangzhou Center alone.
Clinic for Integrative Dentistry, Germany
Keynote: Hyperactivated signaling pathways of chemokine RANTES/CCL5 in osteopathies of jawbone in cancer and autoimmune diseases – Neglected dental cause of systemic diseases?
Time : 10:15-10:45
Johann Lechner is a Dentist and a Naturopath. He is the Head of the Clinic for Integrative Dentistry in Munich, Germany since 1980. He is a Member of Executive Board of DAH (German Association for Research on Disturbance Fields and Regulation) and since 1982 Chairman of GZM (International Society for Holistic Dentistry). He has published numerous articles and nine books in German about holistic dentistry and integrative medicine. His researches focus on silent inflammation in jawbone and the implication to systemic diseases.
Background: Despite significant therapeutic advances most malignancies, as well as adenocarcinomas of the breast, remained incurable. At the same time, the importance of the microenvironment surrounding the tumor cells with "silent inflammation" increases.
Objective: To check the suspected tumor-relevant inflammatory cytokine sources in fatty-degenerative osteonecrotic jaw bone (FDOJ), we analyze these conspicuously altered jawbone areas to assess the expression and quantification of cytokine expression.
Material & Method: In 38 tumor patients we determine the levels of cytokines by bead-based Luminex® analysis in samples of FDOJ.
Results: A high content of chemokine RANTES/CCL5 (R/C) in all 38 jawbone tissue samples of cancer patients was observed. A single case is characterized by high R/C levels in FDOJ sample and simultaneously by metastasizing cells inside the FDOJ sample. The R/C expression in all 38 FDOJ samples on an average were 35 fold higher compared to healthy jawbone.
Discussion: R/C interacts on several levels in immune responses and is considered in scientific literature as pathogenetic key point in tumor growth. The study supports a potential mechanism where FDOJ is a mediating link specifically in breast cancer (MaCa) and its metastasis. R/C is thus involved intensively in oncogenic propulsion progress developments.
Conclusion: The authors conclude from the data of FDOJ analysis that these areas express hyperactivated signal transduction of the chemokine R/C, induce pathogenetic autoimmune processes in tumors, MaCa and its metastasis and serve as a possible cause. The authors hypothesize that such changes in areas of improper and incomplete wound healing in the jawbone may lead to hyperactivated signaling pathways, and result in unrecognized sources of silent inflammation which may contribute to systemic disease patterns like cancer. Combining the R/C signal induction of tumors and the information we collect illustrated, it may be suggested to involve FDOJ in an integrative concept for tumor therapy.